Summary of Study ST001317

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000894. The data can be accessed directly via it's Project DOI: 10.21228/M84D6J This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001317
Study TitleDynamics of Exposure, Phthalates, and Asthma in a Randomized Trial (DEPART)
Study TypeCHEAR Study
Study SummaryProject will investigate relationships between phthalate exposure, pediatric asthma health, and underlying biological pathways of toxicity among a rural, underserved Latino population located in Yakima Valley, WA. DEPART will benefit from the original study’s (HAPI’s) robust longitudinal repeat-measure design and community-engaged framework. DEPART will add new measurements including concentrations of urinary phthalate monoester metabolites and biomarkers of oxidative stress to better characterize exposure-response associations. This project’s primary goal is to deepen the understanding of pathophysiological phenomena underlying exposure-response relationships between phthalates and asthma health. Our specific aims are: (1) Characterize associations between urinary phthalate metabolite concentrations and short-term asthma morbidity, and (2) Determine individual relationships between urinary phthalate metabolite concentrations, short-term asthma morbidity, and biomarkers for oxidative stress to assess the potential for a mediating effect by oxidative stress. Covariates of interest will include atopic status, randomized intervention grouping, and the caregiver psychosocial stress assessment.
Institute
Icahn School of Medicine at Mount Sinai
DepartmentDepartment of Environmental Medicine and Public Health
LaboratoryMount Sinai CHEAR Untargeted Laboratory Hub
Last NameWalker
First NameDouglas
AddressAtran Building RM AB3-39, 1428 Madison Ave
Emaildouglas.walker@mssm.edu
Phone212-241-9891
Submit Date2020-02-05
Raw Data AvailableYes
Raw Data File Type(s)d
Chear StudyYes
Analysis Type DetailLC-MS
Release Date2021-08-31
Release Version1
Douglas Walker Douglas Walker
https://dx.doi.org/10.21228/M84D6J
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id SampleType
SA094784C-1Q7R6-U-00CHEAR Study Sample
SA094785C-1Q7Q8-U-00CHEAR Study Sample
SA094786C-1Q6M8-U-00CHEAR Study Sample
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SA094789C-1Q908-U-00CHEAR Study Sample
SA094790C-1Q2M2-U-00CHEAR Study Sample
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SA094792C-1Q429-U-00CHEAR Study Sample
SA094793C-1Q460-U-00CHEAR Study Sample
SA094794C-1Q6C0-U-00CHEAR Study Sample
SA094795C-1Q3N8-U-00CHEAR Study Sample
SA094796C-1Q5R8-U-00CHEAR Study Sample
SA094797C-1Q4J6-U-00CHEAR Study Sample
SA094798C-1Q544-U-00CHEAR Study Sample
SA094799C-1Q8X1-U-00CHEAR Study Sample
SA094800C-1Q452-U-00CHEAR Study Sample
SA094801C-1Q4P3-U-00CHEAR Study Sample
SA094802C-1Q9C7-U-00CHEAR Study Sample
SA094803C-1Q346-U-00CHEAR Study Sample
SA094804C-1Q8F1-U-00CHEAR Study Sample
SA094805C-1Q2P5-U-00CHEAR Study Sample
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SA094815C-1QAL9-U-00CHEAR Study Sample
SA094816C-1Q3L3-U-00CHEAR Study Sample
SA094817C-1Q247-U-00CHEAR Study Sample
SA094818C-1Q7M7-U-00CHEAR Study Sample
SA094819C-1Q395-U-00CHEAR Study Sample
SA094820C-1Q2H3-U-00CHEAR Study Sample
SA094821C-1QA67-U-00CHEAR Study Sample
SA094822C-1Q5D8-U-00CHEAR Study Sample
SA094823C-1Q3F6-U-00CHEAR Study Sample
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SA094831C-1Q6R7-U-00CHEAR Study Sample
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SA094835C-1Q825-U-00CHEAR Study Sample
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SA094838C-1Q445-U-00CHEAR Study Sample
SA094839C-1Q8A2-U-00CHEAR Study Sample
SA094840C-1Q4V0-U-00CHEAR Study Sample
SA094841C-1Q5U1-U-00CHEAR Study Sample
SA094842C-1Q5Y2-U-00CHEAR Study Sample
SA094843C-1Q3V1-U-00CHEAR Study Sample
SA094844C-1Q3A7-U-00CHEAR Study Sample
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SA094846C-1Q593-U-00CHEAR Study Sample
SA094847C-1Q8M6-U-00CHEAR Study Sample
SA094848C-1Q551-U-00CHEAR Study Sample
SA094849C-1Q5E6-U-00CHEAR Study Sample
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SA094851C-1Q6K2-U-00CHEAR Study Sample
SA094852C-1Q684-U-00CHEAR Study Sample
SA094853C-1Q437-U-00CHEAR Study Sample
SA094854C-1QA18-U-00CHEAR Study Sample
SA094855C-1Q4H1-U-00CHEAR Study Sample
SA094856C-1Q9L7-U-00CHEAR Study Sample
SA094857C-1Q890-U-00CHEAR Study Sample
SA094858C-1Q1U5-U-00CHEAR Study Sample
SA094859C-1Q973-U-00CHEAR Study Sample
SA094860C-1Q783-U-00CHEAR Study Sample
SA094861C-1Q9P8-U-00CHEAR Study Sample
SA094862C-1Q3Y4-U-00CHEAR Study Sample
SA094863C-1Q7D6-U-00CHEAR Study Sample
SA094864C-1Q3S7-U-00CHEAR Study Sample
SA094865C-1Q8Q7-U-00CHEAR Study Sample
SA094866C-1Q4G3-U-00CHEAR Study Sample
SA094867C-1Q3B5-U-00CHEAR Study Sample
SA094868C-1Q3U3-U-00CHEAR Study Sample
SA094869C-1Q205-U-00CHEAR Study Sample
SA094870C-1Q8R5-U-00CHEAR Study Sample
SA094871C-1Q3M1-U-00CHEAR Study Sample
SA094872C-1Q2R1-U-00CHEAR Study Sample
SA094873C-1Q9W3-U-00CHEAR Study Sample
SA094874C-1Q8G9-U-00CHEAR Study Sample
SA094875C-1Q2K6-U-00CHEAR Study Sample
SA094876C-1Q5G2-U-00CHEAR Study Sample
SA094877C-1Q569-U-00CHEAR Study Sample
SA094878C-1Q6A4-U-00CHEAR Study Sample
SA094879C-1Q2F7-U-00CHEAR Study Sample
SA094880C-1Q759-U-00CHEAR Study Sample
SA094881C-1Q6V8-U-00CHEAR Study Sample
SA094882C-1QAA3-U-00CHEAR Study Sample
SA094883C-1QA83-U-00CHEAR Study Sample
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