Summary of Study ST001211

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000814. The data can be accessed directly via it's Project DOI: 10.21228/M8G40M This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001211
Study TitleMetabolomic Markers of Methotrexate Response, In Vitro
Study SummaryErythroblastoid cells (K562) maintained in logarithmic growth phase were treated with 1000 nM methotrexate or vehicle alone (i.e. D-PBS) under standard culture conditions for 24 hours. Cellular response to methotrexate was measured based on anti-proliferative activity by cell counting. Cells were washed, flash frozen in liquid nitrogen and submitted for metabolomics analysis to the NIH West Coast Metabolomics Center.
Institute
University of Kansas
DepartmentPharmacy Practice
LaboratoryFunk Lab
Last NameFunk
First NameRyan
Address2106 Olathe Boulevard
Emailryanfunk@kumc.edu
Phone9135885000
Submit Date2019-07-03
Num Groups2
Total Subjects20 samples
Analysis Type DetailGC-MS/LC-MS
Release Date2020-01-06
Release Version1
Ryan Funk Ryan Funk
https://dx.doi.org/10.21228/M8G40M
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR000814
Project DOI:doi: 10.21228/M8G40M
Project Title:Metabolic Markers of Methotrexate Response
Project Type:In Vitro
Project Summary:Untargeted metabolomics study of methotrexate pharmacological response.
Institute:University of Kansas
Department:Pharmacy Practice
Laboratory:Funk
Last Name:Funk
First Name:Ryan
Address:2106 Olathe Boulevard, Kansas City, Kansas, 66160, USA
Email:ryanfunk@kumc.edu
Phone:9139456904
Funding Source:KL2TR002367
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