Summary of Study ST001211
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000814. The data can be accessed directly via it's Project DOI: 10.21228/M8G40M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001211 |
Study Title | Metabolomic Markers of Methotrexate Response, In Vitro |
Study Summary | Erythroblastoid cells (K562) maintained in logarithmic growth phase were treated with 1000 nM methotrexate or vehicle alone (i.e. D-PBS) under standard culture conditions for 24 hours. Cellular response to methotrexate was measured based on anti-proliferative activity by cell counting. Cells were washed, flash frozen in liquid nitrogen and submitted for metabolomics analysis to the NIH West Coast Metabolomics Center. |
Institute | University of Kansas |
Department | Pharmacy Practice |
Laboratory | Funk Lab |
Last Name | Funk |
First Name | Ryan |
Address | 2106 Olathe Boulevard |
ryanfunk@kumc.edu | |
Phone | 9135885000 |
Submit Date | 2019-07-03 |
Num Groups | 2 |
Total Subjects | 20 samples |
Analysis Type Detail | GC-MS/LC-MS |
Release Date | 2020-01-06 |
Release Version | 1 |
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Project:
Project ID: | PR000814 |
Project DOI: | doi: 10.21228/M8G40M |
Project Title: | Metabolic Markers of Methotrexate Response |
Project Type: | In Vitro |
Project Summary: | Untargeted metabolomics study of methotrexate pharmacological response. |
Institute: | University of Kansas |
Department: | Pharmacy Practice |
Laboratory: | Funk |
Last Name: | Funk |
First Name: | Ryan |
Address: | 2106 Olathe Boulevard, Kansas City, Kansas, 66160, USA |
Email: | ryanfunk@kumc.edu |
Phone: | 9139456904 |
Funding Source: | KL2TR002367 |