Summary of Study ST001211
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000814. The data can be accessed directly via it's Project DOI: 10.21228/M8G40M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001211 |
| Study Title | Metabolomic Markers of Methotrexate Response, In Vitro |
| Study Summary | Erythroblastoid cells (K562) maintained in logarithmic growth phase were treated with 1000 nM methotrexate or vehicle alone (i.e. D-PBS) under standard culture conditions for 24 hours. Cellular response to methotrexate was measured based on anti-proliferative activity by cell counting. Cells were washed, flash frozen in liquid nitrogen and submitted for metabolomics analysis to the NIH West Coast Metabolomics Center. |
| Institute | University of Kansas |
| Department | Pharmacy Practice |
| Laboratory | Funk Lab |
| Last Name | Funk |
| First Name | Ryan |
| Address | 2106 Olathe Boulevard |
| ryanfunk@kumc.edu | |
| Phone | 9135885000 |
| Submit Date | 2019-07-03 |
| Num Groups | 2 |
| Total Subjects | 20 samples |
| Analysis Type Detail | GC-MS/LC-MS |
| Release Date | 2020-01-06 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Subject:
| Subject ID: | SU001278 |
| Subject Type: | Cultured cells |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 53 years |
| Gender: | Female |
| Cell Biosource Or Supplier: | Coriell |
| Cell Strain Details: | GM05372 |
| Cell Primary Immortalized: | Epstein-Barr Virus |
| Cell Passage Number: | Six |
| Cell Counts: | 15 million |
